2006 depauw baseball schedule/RESULTS (20-23, 8-8 SCAC)
| Date | Opponent | Time |
| Feb. 23 | at Anderson | L, 0-1 |
| at Anderson | W, 5-3 | |
| Feb. 26 | TRANSYLVANIA | L, 3-6 |
| TRANSYLVANIA | W, 5-3 | |
| Feb. 28 | MARIAN, IND. (1-9) | W, 7-6 |
| March 4 | BENEDICTINE (1-9) | W, 8-4 |
| March 5 | NORTH PARK (1-9) | W, 17-8 |
| MOUNT ST. JOSEPH (1-9) | L, 3-5 | |
| March 12 | at Manchester | L, 1-3 |
| March 15 | WABASH (1-9) | W, 1-0 |
| March 18 | CONCORDIA, Ill. | W, 4-3 |
| CONCORDIA, Ill. | L, 3-5 | |
| March 19 | ADRIAN | L, 2-8 |
| March 25 | *at Centre | L, 2-3 |
| *at Centre | W, 5-0 | |
| March 26 | *at Centre | L, 2-7 |
| *at Centre | W, 9-7 | |
| March 28 | at Emory | L, 1-8 |
| March 29 | at Piedmont | L, 7-11 |
| March 30 | at LaGrange | L, 1-8 |
| March 31 | *at Oglethorpe | L, 4-5 |
| April 1 | *at Oglethorpe | W, 19-5 |
| *at Oglethorpe | L, 0-2 | |
| April 2 | *at Oglethorpe | L, 7-10 |
| April 5 | FRANKLIN | W, 12-9 |
| April 8 | *ROSE-HULMAN | W, 9-3 |
| *ROSE-HULMAN | L, 3-4 | |
| April 9 | *ROSE-HULMAN | L, 3-11 |
| *ROSE-HULMAN | W, 5-4 | |
| April 12 | vs. Anderson at Victory Field; Indianapolis | L, 1-2 |
| April 13 | FRANKLIN | W, 24-19 |
| April 15 | at Washington, Mo. | L, 1-3 |
| at Washington, Mo. | L, 5-10 | |
| April 18 | at Franklin | L, 8-13 |
| April 22 | *SEWANEE | W, 4-2 |
| *SEWANEE | W, 8-5 | |
| April 23 | *SEWANEE | W, 20-5 |
| *SEWANEE | L, 8-11 | |
| April 27 | $vs. Millsaps (SCAC Championship; hosted by Sewanee) | L, 1-7 |
| April 28 | $vs. Sewanee (SCAC Championship; hosted by Sewanee) | W, 15-1 |
| April 29 | $vs. Rhodes (SCAC Championship; hosted by Sewanee) | W, 18-4 |
| $vs. Millsaps (SCAC Championship; hosted by Sewanee) | L, 1-11 | |
| May 2 | HANOVER | W, 4-3 |
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*Southern Collegiate Athletic Conference game $SCAC Championship hosted by Sewanee |
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| Postponed games: March 11 at Hanover (2); March 22 at Wabash (1) | ||