2001 depauw football schedule/results (5-5, 4-2 scac)
| Sept. 1 | *RHODES (Community Day) | W, 38-17 |
| Sept. 8 | at Hanover | L, 27-30 |
| Sept. 15 | at Hope | L, 21-41 |
| Sept. 22 | *at Trinity | L, 18-52 |
| Oct. 6 | *at Sewanee | W, 34-18 |
| Oct. 13 | BLACKBURN | W, 35-8 |
| Oct. 20 | *MILLSAPS | W, 32-7 |
| Oct. 27 | *CENTRE (Old Gold/Hall of Fame) | L, 31-34 (OT) |
| Nov. 3 | *at Rose-Hulman | W, 45-22 |
| Nov. 10 | WABASH (Monon Bell) | L, 21-27 |
| *Southern Collegiate Athletic Conference game | ||