2005 Depauw men's soccer schedule/results (11-4-2, 6-2-1 SCAC)
| Date | Opponent | Time |
| Sept. 2 | HOPE | W, 3-1 |
| Sept. 3 | KALAMAZOO | T, 1-1 (2 ot) |
| Sept. 10 | at Earlham | W, 5-3 |
| Sept. 11 | at Wittenberg | L, 0-2 |
| Sept. 17 | at Ohio Wesleyan | L, 1-4 |
| Sept. 21 | at Wabash | W, 5-2 |
| Sept. 24 | FRANKLIN | W, 6-0 |
| Oct. 1 | *ROSE-HULMAN | W, 1-0 |
| Oct. 7 | *SOUTHWESTERN | W, 1-0 |
| Oct. 9 | *TRINITY | L, 1-3 |
| Oct. 14 | *at Millsaps | W, 3-0 |
| Oct. 16 | *at Oglethorpe | L, 0-3 |
| Oct. 21 | MILLIKIN | W, 4-0 |
| Oct. 28 | *SEWANEE | W, 4-2 |
| Oct. 30 | *CENTRE | T, 1-1 (2 ot) |
| Nov. 4 | *at Hendrix | W, 3-1 |
| Nov. 6 | *at Rhodes | W, 3-0 |
| *Southern Collegiate Athletic Conference games | ||