Mark Kelley '79 Publishes DNA Repair in Cancer Therapy

Mark Kelley '79 Publishes DNA Repair in Cancer Therapy

September 9, 2011

99755September 9, 2011, Greencastle, Ind. — Mark R. Kelley, Betty and Earl Herr Chair in Pediatric Oncology Research at the Indiana University School of Medicine and 1979 graduate of DePauw University, is editor of DNA Repair in Cancer Therapy: Molecular Targets and Clinical Applications. Dr. Kelley also contributes two chapters to the new book, which is published by Academic Press.

"Cancer therapeutics include an ever-increasing array of tools at the disposal of clinicians in their treatment of this disease," states a synopsis of the book. "However, cancer is a tough opponent in this battle, and current treatments, which typically include radiotherapy, chemotherapy and surgery, are not often enough to rid the patient of his or her cancer. Cancer cells can become resistant to the treatments directed at them, and overcoming this drug resistance is an important research focus. Additionally, increasing discussion and research is centering on targeted and individualized therapy ... This comprehensive and timely reference focuses on the translational and clinical use of DNA repair as a target area for the development of diagnostic biomarkers and the enhancement of cancer treatment."

99756In the book's acknowledgments, Kelly thanks, among others, his wife, Susan (Wexelberg) Kelley '79, "who has always encouraged me in my work and career even as far back as our college days at DePauw University."

Learn more, and order the book, at

Mark Kelley also serves as associate director of the Herman B Wells Center for Pediatric Research, the associate director of basic science research at Indiana University's Simon Cancer Center, and is director of the program in molecular pediatric oncology.

Also available is this previous story on Dr. Kelley.